ATG16L1 and Crohn disease: In humans, 16 different single nucleotide variants (SNPs) located within the Atg16l1 gene and in an intergenic region between the Atg16l1 and Scarna5 genes have been associated with inflammatory bowel disease, ulcerative colitis, and Crohn’s disease (Buniello et al., 2019; Liu et al., 2015; Franke et al., 2010; Julia et al., 2013).