In addition, in the KEGG pathway analysis, 155 KEGG pathways were selected (P-adjust < 0.05) related to all predicted targets, including the drug metabolism-cytochrome P450, metabolism of xenobiotics by cytochrome P450, prolactin signaling pathway, chemical carcinogenesis, platinum drug resistance, prostate cancer, non-small cell lung cancer, EGFR tyrosine kinase inhibitors, adherens junctions, PPAR signaling pathway, fluid shear stress and atherosclerosis, arachidonic acid metabolism, adipocytokine signaling pathway, and tyrosine metabolism (Figure 2H). Here, PRL is linked to Familial prostate cancer.