VEGFA and glioblastoma: It has been reported that β1 4-galactosyltransferase I (B4GalT1) expression is significantly increased in GBM and plays a significant role in inflammatory activation and regulation of apoptosis [28], and other studies have reported that SB365 can inhibit the growth of GBM cells and induce morphological characteristics of cell tendency to apoptosis, such as nuclear condensation and fragmentation, enhanced expression of caspase-3, and significantly delayed cell migration and decreased HIF-1α expression and VEGF secretion [29].