Lin et al. [49] also showed that BP decreased the cell viability and induced cell cycle arrest in colorectal cancer cells, which may be attributed to p53-mediated apoptotic cascade, upregulation of p21 and PTEN (phosphatase and tensin homolog), and inhibition of Akt [49] (Lin, 2019 #20). The gene discussed is PTEN; the disease is colorectal cancer.