Early-stage atherosclerosis formation involves flow-mediated inflammatory changes in the endothelial cells (ECs), and when ECs are damaged, inflammatory factors such as monocyte chemotactic protein-1, interleukin (IL)-8, vascular adhesion molecule-1, E-selectin and P-selectin are released, which attract lymphocytes and monocytes that infiltrate the arterial wall and lead to inflammation [10]. Here, CCL2 is linked to atherosclerosis.