Although menin can suppress tumorigenesis in the endocrine lineage, it can also promote oncogenic function in other tissues, such as breast.(42) In the hematopoietic lineage, menin serves as a molecular adaptor that physically links the mixed‐lineage leukemia (MLL) histone methyltransferase with lens epithelium‐derived growth factor (LEDGF), a chromatin‐associated protein implicated in leukemia.(43) Binding of menin to MLL1 leads to upregulation of Hox gene transcription and leukemia in MLL‐rearranged acute myeloid leukemia (AML) and acute lymphocytic leukemia (ALL).(44). The gene discussed is PSIP1; the disease is acute lymphoblastic leukemia.