YTHDF2 inhibits the proliferation and growth of HCC cells by disrupting the stability of epidermal growth factor receptor mRNA [12], and YTHDF3 negatively regulates the interaction between two long noncoding RNAs, growth arrest-specific 5 (GAS5) and yes-associated protein (YAP) and ultimately inhibits CRC progression [13]. The gene discussed is GAS5; the disease is colorectal carcinoma.