Li et al. evaluated the value of miR-146a and miR-146b in AP, and found that among patients with SAP, MSAP and MAP, the expression levels of miR-146a and miR-146b were highest in SAP patients and were closely related to the Ranson's score, APACHE II score, SOFA score and C-reactive protein (CRP) level. The gene discussed is CRP; the disease is alkaline phosphatase measurement.