What is more, although patients with MYLK3 methylation showed prolonged overall survival in ovarian cancer, there was no statistically significant association between expression of the gene and overall survival in these patients [45], while it is exciting that ATP2A1 mRNA and protein are overexpressed in ovarian cancer tissues compared to normal ovarian surface epithelial cell [46, 47]. This evidence concerns the gene ATP2A1 and ovarian cancer.