Up to now, studies have shown that there are many factors affecting liver fibrosis under resveratrol treatment, including the key signaling pathways, such as the hippo pathway and PI3K/AKT pathway, and the anti-oxidative and anti-inflammatory effects(Yu 2019; Chen et al. 2020; Hessin et al. 2017; Vairappan et al. 2019). This evidence concerns the gene AKT1 and Hepatic fibrosis.