RIPK2 and neoplasm: In KIRC, the expression of RIPK2 was negatively related to tumor purity (r = − 0.21, p < 0.001), B cell (r = 0.35, p < 0.001), macrophage (r = 0.30, p < 0.001), and neutrophil (r = 0.46, p < 0.001).