WNT3A and type 2 diabetes mellitus: The current study represents the first effort using the combination of in vitro and in vivo silencing technique to identify the role of Wnt3a in PEMF-mediated regulation of bone metabolism, which provides full evidence that Wnt3a-mediated (rather other canonical/non-canonical Wnt ligands) downstream β-catenin activation plays an essential role in PEMF-induced bone anabolism in pathological T2DM conditions.