Our Western blot analysis of NR2E3 in retinoblastoma cells showed that biliverdin induced the level of NR2E3 protein by approximately twofold (2.0 ± 0.2 fold elevation by 1 μM biliverdin, n = 3; Fig. 3C, S5) in a dose-dependent manner (Fig. 3D, not repeated). This evidence concerns the gene NR2E3 and retinoblastoma.