There were no significant changes in the median fluorescence intensity of activation marker CD158 among healthy and COVID-19 subjects (data not shown), which was associated to the amount of IL-6 (r-square = 0.61, p = 0.004) and TGF-β (r-square = 0.46, p = 0.004), but not of IL-1β, IL-17A TNF-α or IFN-γ evaluated at hospital admission (data not shown). This evidence concerns the gene IL1B and COVID-19.