APOE and infection: Thus, to determine a putative association between APOE isoform and SARS-CoV-2infection, we next evaluated the combination of the two SNPs rs7412 and rs429358 in the risk of infection by mean of an ordinal logistic model with the same covariables as before, by using a model that included two variables representing the number of ε2 and ε4 alleles, respectively, in the genotype.