Major Major CD CD Gao Gao ZY ZY Wolf Wolf BA BA Activation of the sphingomyelinase/ceramide signal transduction pathway in insulin-secreting beta-cells: role in cytokine-induced beta-cell death Activation of the sphingomyelinase/ceramide signal transduction pathway in insulin-secreting beta-cells: role in cytokine-induced beta-cell death Diabetes Diabetes 07 07 1999 1999 48 48 7 7 1372 1372 1380 1380 10.2337/diabetes.48.7.1372. This evidence concerns the gene INS and diabetes mellitus.