In this study, based on KEGG pathway enrichment analysis and GSEA analysis, the expression levels of ILF3 could regulate the activation of the PI3K/AKT/mTOR signaling pathway The PI3K/AKT/mTOR signaling pathway is important in tumor progression, including cell proliferation, invasion, metastasis, cell cycle, apoptosis, and metabolic functions [84, 85]. This evidence concerns the gene AKT1 and neoplasm.