KEGG pathway analysis of ILF3 identified 14 statistically significant signaling pathways, including African trypanosomiasis, Glycine, serine and threonine metabolism, Mineral absorption, Tryptophan metabolism, Arrhythmogenic right ventricular cardiomyopathy (ARVC), Gap junction, Hypertrophic cardiomyopathy (HCM), Systemic lupus erythematosus, Alcoholism, signaling pathways regulating stem cell pluripotency, TGF-beta signaling pathway, Dilated cardiomyopathy (DCM), Glycosaminoglycan biosynthesis - heparan sulfate / heparin and mTOR signaling pathway (Figure 4A and Supplementary Table 3). The gene discussed is ILF3; the disease is alcohol dependence.