TLR8 and neonatal encephalopathy: In the previously mentioned study by Lucchi et al, the authors observed elevated expression of PPARγ in the same group of interneurons herein described for TLR8 (i.e. SOM, PARV) and Balada et al. [40] showed that in patients with neonatal encephalopathy the expression of PPARγ and TLR8 (during the first 4 days of life) was increased in relation to controls.