For instance, one submitter may assert a limited role in ‘breast cancer’ for BRIP1 and another may assert a definitive role in ‘breast and ovarian cancer’ for BRIP1 and these claims may both be valid given that BRIP1 is validly implicated in ovarian cancer but not breast cancer.16–18 To begin these efforts, we have calculated some gene-disease validity term conflict statistics from the database. The gene discussed is BRIP1; the disease is ovarian carcinoma.