CD40LG and schizophrenia: In schizophrenia, Maes, Kanchanatawan, Sirivichayakul, and Carvalho (2019a) and Maes, Sirivichayakul, Kanchanatawan, and Vodjani (2019b) showed that immunoglobulin M (IgM) responses to zonulin were higher in patients compared to controls, while IgM response to occludin was significantly associated with deficit schizophrenia.