Reduced expression of lncRNA plasmacytoma variant translocation 1 (PVT1) was observed in the placentas of patients with GDM and preeclampsia, and knocking down PVT1 enhanced apoptosis and inhibited the proliferation, migration, and invasion of trophoblast cells through the PI3K/Akt pathway [6]. Here, PVT1 is linked to preeclampsia.