Although our model resembled human GD-TCL based on TCR-γ expression, it also possesses several common features that are generally observed in mature T-cell neoplasms, such as high level of expression of GATA3 and MYC, and the infiltration of tumor cells into the surrounding tissues and distal organs, in particular, cutaneous regions. The gene discussed is TRGC1; the disease is T-cell and NK-cell neoplasm.