To identify novel biomarkers in cutaneous melanoma, we used an integrative bioinformatics analysis, combining our previous identified pan-cancer deregulated genes (DEGs) with web-source available datasets in CM.15 Six shared DEGs were identified, including SVEP1, WIF1, PAMR1, SLIT3, MRGPRF and CCBE1 (Fig. 1a, Supplementary Table S1). This evidence concerns the gene WIF1 and cancer.