Our study found that up-expressed hsa-mir-183 and over transcriptional expressions of hsa-mir-183 predicted target genes (ENY2, PLAG1, PDCD6, GNG5, SLC6A6, CELSR3, SLC22A23, SPATS2, CDK5R1, PHF6, MAL2, ATP2C1, NRAS, SLC25A15 and PTDSS1) were observed in BLCA patients. This evidence concerns the gene MAL2 and bladder transitional cell carcinoma.