Immunoblot analysis of tumor lysates revealed a marked increase in p-mTOR (S2448), p-P70S6K (T389), and p-S6 (S235/S236) expression levels in etoposide-treated xenografts, whereas addition of FX1 suppressed the activation of the mTOR signaling pathway (Figure 7B). This evidence concerns the gene RPS6KB1 and neoplasm.