Recently, a small imaging series by our group was performed using the human U87 glioma cell line stably transfected with a NIS expressing plasmid (CMV-NIS-pcDNA3) (U87-NIS) to track the tumoral NIS expression of s.c. and orthotopic brain tumors by a direct comparison of 124I and [18F]TFB as radiotracers for small animal PET imaging. Here, SLC5A5 is linked to glioma.