Similarly to the ex vivo data, we observed a concomitant, significant decrease in MFI for both HLA-I molecules (HLA-A/-B/-C subsets) and β-2 microglobulin (β2m) in high-and low-grade cancer cells 24 hours after BCG coincubation (Figure 1G and Supplemental Figure 1, F and G). The gene discussed is B2M; the disease is cancer.