Reflecting this promise, more than 24 clinical trials have been conducted or initiated investigating Hsp90 NTD inhibitors for the treatment of cancer (Jhaveri et al., 2014 ▸; Garcia-Carbonero et al., 2013 ▸; Zagouri et al., 2013 ▸; Neckers & Workman, 2012 ▸). This evidence concerns the gene HSP90AB1 and cancer.