HSP90AA1 and cancer: Since the overexpression or accumulation of misfolded proteins is associated with many diseases such as cancer, neurodegenerative and infectious diseases, inhibition of Hsp90 has been pursued as a promising method for their treatment (Chaudhury et al., 2006 ▸; Shrestha et al., 2016 ▸; Wang et al., 2017 ▸; Alam et al., 2017 ▸; Ekman et al., 2010 ▸; Augello et al., 2019 ▸; Buc Calderon et al., 2019 ▸; Garg et al., 2016 ▸).