Serum NfL was significantly higher in the total pre‐MS group, with a geometric mean level of 7.1 pg/mL (CI 6.8–7.4) compared with 6.2 pg/mL (CI 5.9–6.5) in the control group (p = 0.00001, Fig. 1B). This evidence concerns the gene NEFL and myeloid sarcoma.