And then, we used MCC algorithm to find out the top 6 Hub genes of DO as a treatment for hyperlipidemia (Figure 3(c)), which were RAC-alpha serine/threonine-protein kinase (AKT1), Tumor necrosis factor (TNF), Peroxisome proliferator activated receptor gamma (PPARG), Adiponectin (ADIPOQ), Apolipoprotein B-100 (APOB), and Nitric-oxide synthase endothelial (NOS3). Here, TNF is linked to hyperlipidemia.