In this study, we have identified a few commonly mutated genes in pre-NACT tumor samples from either sensitive (DNAH5, CYP2D6, NUTM1) or resistant (CSPG4, TUBA3D, SLC35G5) cases, which suggest that these genes could have a potential utility for prediction of the response to NACT. The gene discussed is DNAH5; the disease is neoplasm.