The amplification of chromosome 19, where resides Cyclin E gene is the eight most common copy number amplified gene analyzed in all ovarian cancer samples included in The Cancer Genome Atlas (TCGA) [13] and has been identified as a primary oncogenic driver in a subset of high grade serous ovarian cancer that are resistant to chemotherapy [27, 31]. This evidence concerns the gene CCNE1 and ovarian serous adenocarcinoma.