Therefore, we explored the association between STK10 expression and these ligands on the surface of AML cells, such as HLA-A, HLA-B, HLA-C, HLA-E, PD-L1(CD274), PD-L2 and GAL-9(produced by LGALS9), etc. Among them, HLA-E, CD274 and LGALS9 were overexpressed on tumor cells (Fig. 8a, d, g) and predicted poor OS in AML (Fig. 8b, e, h). This evidence concerns the gene PDCD1LG2 and acute myeloid leukemia.