Excessive production of cytokines such as interleukin-1 beta (IL-1β), IL-6, and tumor necrosis factor-alpha (TNF-α) has been shown to result in a virus-induced hyperinflammatory condition known as the cytokine storm, which is associated with severe COVID-19 complications and an aggravation of lung pathology [115]. This evidence concerns the gene TNF and COVID-19.