Moreover, the Pearson method was used to analyze the correlation between miR-182-5p and BDNF, and the results unveiled the prominently inverse association of miR-182-5p expression and BDNF level in the serum of CHF patients (r = −0.635, P < 0.001) (Fig. 2D). The gene discussed is BDNF; the disease is congestive heart failure.