The T24 cells with or without ZBTB7A knockdown were implanted in nude mice and we found that, compared with control cells, loss of ZBTB7A significantly suppressed the growth of T24 xenograft tumors, as indicated by tumor weight and size reduction (Fig. 1J–L), also the downregulation of ZBTB7A was confirmed by Western blotting in tumor xenografts (Additional file 1: Fig S1C). The gene discussed is ZBTB7A; the disease is neoplasm.