MICALL2 and colon adenocarcinoma: The results showed that high MICAL-L2 expression was negatively correlated with OS (n = 453, P = 0.006; Fig. 3A) and DSS (n = 437, P = 0.028; Fig. 3B), indicating that MICAL-L2 expression levels were significantly associated with the prognosis of COAD patients.