However, Komatsu et al. described that hepatic steatosis occurs in patients afflicted with citrullinemia type 2 (CTLN2), an autosomal recessive disorder caused by a mutation in the gene encoding mitochondrial aspartate glutamate carrier 2 (SLC25A13) and these patients were not categorized as obese [100]. This evidence concerns the gene SLC25A13 and citrullinemia type II.