MAPK14 and neoplasm: p38 inhibition not only decreases expression of stemness factors and compromises intravasation, distant colonization, and survival of circulating tumor cells, but it would also push metastatic, mesenchymal-like tumor cells into an epithelial state by inducing the mesenchymal-to-epithelial transition, thereby rendering them chemosensitive [34, 105, 106].