LAG3 and coronary artery disorder: In FHS, while there were no associations at FDR < 0.05 for CHD, we observed that 18 of the 183 LAG3-associated proteins demonstrating FDR < 0.05 were significantly associated with all-cause mortality based on two-sided Z-tests for the coefficients from Cox regression with a total sample of n = 1913, including 650 events (Supplementary Data 12).