In hepatocellular carcinoma, it was also reported that POH1 expression at the protein level correlates with a molecular signature associated with metastatic potential in vitro and in vivo, and it was suggested that this might be mediated by the effect of POH1 on the transforming growth factor (TGF)-beta signalling pathway that is dysregulated in the progression of hepatocarcinoma [84]. The gene discussed is PSMD14; the disease is hepatocellular carcinoma.