FIBCD1 and cancer: Further testing of one of these myokines, secreted Fibcd1 (Fibrinogen C Domain-Containing Protein 1), determined its evolutionary-conserved role in myofiber size regulation in mice, and that recombinant Fibcd1 (rFibcd1) mitigates myofiber atrophy associated with cancer cachexia in the diaphragm muscle.