As demonstrated by western blotting in Fig. 2A, UHMK1 expression varied in CRC cell lines, both RKO and HCT116 showed high protein expression, while SW620, Caco-2, HT29, LoVo, DLD-1, and SW480 had relatively low UHMK1 expression. The gene discussed is UHMK1; the disease is colorectal carcinoma.