YAP1 and cystic fibrosis: Considering the selectivity of the YAP1–F508del–CFTR interaction, as well as the consistent rescue of the F508del-CFTR traffic phenotype in response to YAP1 KD–siYAP1 (1)/(2), siTEAD4 (1) + siYAP1 (1)/(2) – YAP1 was classified as the most promising hit, and we sought to further characterize its role in EMT induction in CF models.