HSP90AB1 is a molecular chaperone with roles in tumorigenesis (63) that activates the Wnt/β-catenin signaling pathway in gastric cancer (64) that also enhances the TGF-β/SMAD signaling in lung adenocarcinoma (LUAD) (65), promoting EMT in both scenarios. The gene discussed is TGFB1; the disease is lung adenocarcinoma.