DCLK3 and infection: Upon the assessment of humoral responses, the CLR+CFA+GLA-SE/CDG group exhibited more enhanced CFA-specific IgG2a and IgG2b responses, which are generally related to Th1 responses [60], than the CLR monotherapy group (p < .05) (Supplementary Figure S10), but these responses did not contribute to enhancing the therapeutic efficacy against Mav infection.