RUNX2 and breast cancer: The expression of miR-153 has been found to promote apoptosis by targeting HECT domain E3 ubiquitin protein ligase 3 (HECTD3) [93] and inhibit proliferation and migration through suppressing runt-related transcription factor 2 (RUNX2) [92] and impaired zinc finger E-box-binding homeobox 2 (ZEB2)-mediated EMT [94] in BC cells.