Phosphoinositide 3-kinase (PI3K)/AKT/mTOR/ vascular endothelial growth factor (VEGF), mitogen-activated protein kinase (MAPK), signal transducers and activators of transcription 3 (STAT3), and Notch are major signaling pathways that could be affected by angioregulatory miRNA in BC. The gene discussed is AKT1; the disease is breast cancer.