Compared with poor-quality blastocysts (236/727), good-quality blastocysts (117/186) (62.90% vs. 32.46%; OR 2.818, 95% CI 1.401–5.665; P=0.004) and average-quality blastocysts (184/394) (46.70% vs. 32.46%; OR 1.669, 95% CI 1.286–2.166; P< 0.001) yielded significantly higher euploidy rates after adjusting for blastocyst developmental rate, maternal age, maternal BMI, duration of infertility, type of infertility, infertility diagnosis, number of prior pregnancies, indication for PGT-A and basal FSH. This evidence concerns the gene BRD2 and Infertility.