After adjusted for other covariates, sex (male vs. female patients: HR = 5.70, 95% CI = 1.06–30.56, p = 0.042), tumor size (≤2 vs. >2 cm: HR = 6.85, 95% CI = 1.11–42.13, p=0.038), and treatment (SRS/EXRT only vs. combine: HR = 29.82, 95% CI = 1.17–760.52, p = 0.040) had significant effect for achieving GH <1 ng/ml. The gene discussed is GH1; the disease is neoplasm.