In the non-NAFLD with IR group, miR-150-5p was positively correlated with TC and LDL-C, miR-155-5p was positively correlated with insulin but negatively with adiponectin, miR-22-3p level was negatively correlated with adiponectin, and miR-27a-3p was negatively correlated with insulin and TG. The gene discussed is INS; the disease is metabolic dysfunction-associated steatotic liver disease.