KCNQ1OT1 and ischemic stroke: Such a lncRNA, lncRNA KCNQ1OT1 has been implicated in many types of human diseases; specifically, KCNQ1OT1 was significantly upregulated in ischemic stroke, and its knockdown reduces infarct volume and neurological impairments in transient middle cerebral artery occlusion (tMCAO) mice [13].